THE INCIDENCE, MAGNITUDE, and duration of acute pain experienced by ne
urosurgical patients after various brain operations are not precisely
known, because of a lack of well-designed clinical and epidemiological
studies. We assessed these important pain variables in 37 consecutive
patients who underwent various brain neurosurgical procedures. Postop
erative pain was more common than generally assumed (60%). In two-thir
ds of the patients with postoperative pain, the intensity was moderate
to severe. Pain most frequently occurred within the first 48 hours af
ter surgery, but a significant number of patients endured pain for lon
ger periods. Pain was predominantly superficial (86%), suggesting soma
tic rather than visceral origin and possibly involving pericranial mus
cles and soft tissues. Subtemporal and suboccipital surgical routes yi
elded the highest incidence of postoperative pain. Age and sex were si
gnificantly associated with the onset of pain, with female and younger
patients reporting higher percentages of postoperative pain. Psycholo
gical Minnesota Multiphasic Personality Inventory profiles of patients
with and without pain significantly differed on the Hypochondriasis s
cale, with patients without pain scoring unexpectedly higher than pati
ents with pain. It is possible that hypochondriasis serves as a defens
e mechanism against pain, at least in some patients. Results of this p
ilot study indicate that postoperative pain after brain surgery is an
important, although neglected, clinical problem, that deserves greater
attention by surgical teams, to provide better and more appropriate t
reatment.