SCAVENGING EFFECTS OF PHENYLPROPANOID GLYCOSIDES FROM PEDICULARIS ON SUPEROXIDE ANION AND HYDROXYL RADICAL BY THE SPIN-TRAPPING METHOD(95)02255-4

The scavenging activities of six phenylpropanoid glycosides, i.e. leuc osceptoside A and martynoside isolated from Pedicularis alashanica Max im, verbascoside, and pediculariosides A, M and N isolated from Pedicu laris striata Pall ssp. arachnoidea Franch Tsoong, on superoxide anion and hydroxyl radicals have been studied by the spin trapping method. The results demonstrated that the number of phenolic hydroxyl groups i n the structures of the phenylpropanoid glycosides is related to their scavenging activities. The scavenging effects of the phenylpropanoid glycosides possessing two o-dihydroxyl groups were stronger than the e ffects of the compounds possessing two o-hydroxy-methoxy groups.