NITRILE OXIDE CYCLOADDITION OF NONACTIVATED ALKYNES - A NOVEL-APPROACH TO THE SYNTHESIS OF NEUROACTIVE ISOXAZOLES

Authors
PEVARELLO P AMICI R COLOMBO M VARASI M
Citation
P. Pevarello et al., NITRILE OXIDE CYCLOADDITION OF NONACTIVATED ALKYNES - A NOVEL-APPROACH TO THE SYNTHESIS OF NEUROACTIVE ISOXAZOLES, Journal of the Chemical Society. Perkin transactions. I, (18), 1993, pp. 2151-2152
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
18
Year of publication
1993
Pages
2151 - 2152
Database
ISI
SICI code
0300-922X(1993):18<2151:NOCONA>2.0.ZU;2-U
Abstract
A general method for the unprecedented 1,3-dipolar cycloaddition of br omonitrile oxide to disubstituted non-activated alkynes provides a use ful alternative route to the neuropharmacological tools AMPA and 4-met hylhomoibotenic acid.