CL307-24, A NEW ANTIBIOTIC COMPLEX FROM SACCHAROPOLYSPORA-AURANTIACA SP-NOV .2. PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

Authors
FABRE B VELOURS J ETIENNE G LEGENDRE F TIRABY G
Citation
B. Fabre et al., CL307-24, A NEW ANTIBIOTIC COMPLEX FROM SACCHAROPOLYSPORA-AURANTIACA SP-NOV .2. PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES, Journal of antibiotics, 46(9), 1993, pp. 1421-1427
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy",Immunology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
46
Issue
9
Year of publication
1993
Pages
1421 - 1427
Database
ISI
SICI code
0021-8820(1993)46:9<1421:CANACF>2.0.ZU;2-O
Abstract
CL307-24I, the main component of the CL307-24 complex produced by Sacc haropolyspora aurantiaca sp. nov., was found to be a potent inhibitor of yeast mitochondrial ATPase. CL307-241 displayed a high degree of ac tivity towards some coryneform bacteria and also has been shown to pos sess an insecticidal activity. Its biological and physico-chemical pro perties clearly distinguish it from previously known ATPase inhibitors .