Stimulated by a severe organ shortage and an improving ability to succ
essfully transplant poorly matched donor-recipient pairs, many transpl
ant centers are now willing to accept emotionally related (but genetic
ally unrelated) people (e.g., spouses) as kidney donors, To see whethe
r this practice is encouraged, a survey was mailed to all 209 adult re
nal transplant centers in the United States. Of the 154 (74%) respondi
ng centers, 90% said they accept emotionally related donors and 60% sa
id they actually encourage this practice, Nearly 40% prefer spouses to
cadavers, while only 21% prefer friends to cadavers. To further explo
re the degree to which emotionally related donation is encouraged, a s
econd questionnaire was sent to a sample of centers (n=51) that suppor
t this practice; 94% responded. While only 44% said they encourage the
use of friends, nearly all of these preselected centers said they enc
ourage spouses to donate, On the other hand, judging from their stated
approach to this issue, only about half of these supportive centers s
eem to actively encourage emotionally related donation, These data sug
gest that, overall, at most only about one third of U.S. transplant ce
nters actively encourage spousal donation and at most about one quarte
r encourage the use of friends. Consistent with these results, emotion
ally related donors contribute only a small fraction of all kidneys tr
ansplanted in this country. If the large potential. contribution of em
otionally related donors is ever to be realized, transplant centers mu
st go beyond simply accepting such individuals and begin to actively e
ncourage their participation. Medical and ethical considerations stron
gly support this proposal.