PSEUDOEPITHELIOMATOUS, KERATOTIC AND MICACEOUS BALANITIS - CASE-REPORT AND REVIEW OF THE LITERATURE

A case of pseudoepitheliomatous, keratotic and micaceous balanitis (PE KMB) in a 64-year old man is presented. The patient presented with the 2-year history of a slowly enlarging, hyperkeratotic plaque on his gl ans penis that was compatible with a clinical diagnosis of PEKMB. The lesion has been treated successfully with topical 5-fluorouracil cream , with no evidence of recurrence at 2-year follow-up. Histological exa mination revealed acanthosis, hyperkeratosis, and pseudoepitheliomatou s hyperplasia with no cytological atypia. This rare penile condition w as considered pseudomalignant, premalignant, or as a low-grade squamou s malignancy. Apart from this patient we comprehensively review previo usly reported cases, and discuss a possible concept on etiology, diagn osis and treatment of this entity.