Ss. Dritz et al., GROWTH AND MICROBIAL-FLORA OF NONMEDICATED, SEGREGATED, EARLY WEANED PIGS FROM A COMMERCIAL SWINE OPERATION, Journal of the American Veterinary Medical Association, 208(5), 1996, pp. 711
Objective-To determine whether segregated, early weaned pigs have bett
er growth performance and different microbial flora than those of pigs
raised on-site.Design-Prospective, observational study. Animals-Pigs
from a commercial operation that were known to be infected with severa
l common swine pathogens. Procedure-Pigs (7 to 10 days old) were weane
d and segregated from the farm of origin and compared with littermate
control pigs (14 to 17 days old) that were weaned and raised on-site.
Pig weight was measured and microbial flora were isolated at 14-day in
tervals for 84 days, beginning when the pigs were 7 to 10 days old. Re
sults-At 50 days of age, the segregated, early weaned pigs had a mean
weight of 23.7 kg, compared with a mean weight of 12.5 kg for control
pigs. Pasteurella multocida was isolated from fewer segregated, early
weaned pigs than from controls. Signs of Mycoplasma hyopneumoniae infe
ction were detected in control pigs but not in segregated early weaned
pigs. Clinical, serologic, or bacteriologic signs of early postnatal
vertical transmission of Actinobacillus pleuropneumoniae were not dete
cted in either group. Clinical Implication-Vertical transmission of M
hyopneumoniae was prevented by weaning pigs at 7 to 10 days of age and
segregating them off-site, without the use of medication. Although me
dicated controls were not compared, results from this herd revealed th
at use of antibiotics is not the most important factor for disease con
trol in segregated, early weaning programs. Minimizing antibiotic use
in disease-control protocols reduces costs as well as removes the need
for extra-label drugs.