PRACTICAL TOTAL SYNTHESIS OF SYL)-N-HEXACOSANOYL-2-AMINO-1,3,4-OCTADECANETRIOL, THE ANTITUMORIAL AND IMMUNOSTIMULATORY ALPHA-GALACTOSYLCERAMIDE, KRN7000
M. Morita et al., PRACTICAL TOTAL SYNTHESIS OF SYL)-N-HEXACOSANOYL-2-AMINO-1,3,4-OCTADECANETRIOL, THE ANTITUMORIAL AND IMMUNOSTIMULATORY ALPHA-GALACTOSYLCERAMIDE, KRN7000, Bioscience, biotechnology, and biochemistry, 60(2), 1996, pp. 288-292
A practical total synthesis of osyl)-N-hexacosanoyl-2-amino-1,3,4-octa
decanetriol (KRN7000), an antitumorial and immunostimulatory glycosphi
ngolipid derived from agelasphins, was achieved in 14 steps starting f
rom D-lyxose in a 16% overall yield.