B. Hess et A. Mikhailov, TRANSITION FROM MOLECULAR CHAOS TO COHERENT SPIKING OF ENZYMATIC-REACTIONS IN SMALL SPATIAL VOLUMES, Biophysical chemistry, 58(3), 1996, pp. 365-368
Theoretical study of an irreversible enzymic reaction with allosteric
product activation reveals that, in small spatial volumes, it can unde
rgo a transition to coherent spiking regime characterized by the prese
nce of strong correlations between reaction events and the states of i
ndividual enzyme molecules.