CONTRIBUTION OF POSITON EMISSION TOMOGRAP HY IN A PATIENT WITH MARCHIAFAVA-BIGNAMI DISEASE - LAMINAR SCLEROSIS OF MOREL

We report the case of a 26-year old alcoholic woman who abruptly prese nted with confusion associated with a major hypertonia. She evolved in to a chronically vegetative state. Magnetic resonance imaging (MRI) wa s consistent with the diagnosis of Marchiafava Bignami disease. The co rpus callosum first presented an oedematous aspect, then a central atr ophy with an axial band. The clinical presentation and the functional imaging strongly suggest an association between the Marchiafava Bignam i disease and diffuse cortical lesions, such as the laminar sclerosis of Morel.