Aim-To determine the prevalence of cerebral palsy in a specific popula
tion. Methods-Multiple sources of ascertainment were used to create an
d maintain a register of all cases of cerebral palsy born to mothers r
esident in the counties of Merseyside and Cheshire in the years 1966 t
o 1989. Denominator data of infant births and deaths from 1966 to 1981
were obtained from statutory notifications made to health authorities
and, for the period 1982-89, from statutory birth and death registrat
ions. Over 1500 cases formed the database for the study. Results-The p
revalence of cerebral palsy has increased among all the low birthweigh
t groups with, most recently, an increase in infants weighing <1000 g
at birth. Low birthweight infants now comprise about 50% of all cases
of cerebral palsy; in the early years of the study they comprised abou
t 32% of all cases. The proportion of cerebral palsy by clinical type
has changed among low birthweight babies, with relatively fewer cases
with diplegia and a concomitant increase in the proportion with hemipl
egia. An increase in the severity of functional disability, determined
by the proportion of children with severe learning, manual, and ambul
atory disabilities, was also found. Conclusions-The change in the epid
emiology of cerebral palsy has implications for the aetiology of the c
ondition, and for health, educational, and social service provision.