THE EFFECT OF 2-CHLOROADENOSINE ON THE ATP LEVEL NA,K-ATPASE ACTIVITYIN EXPERIMENTAL BRAIN ISCHEMIA OF GERBIL

Authors
TURKOZKAN N AYKOL S BILGIHAN A YAVUZ O CAYCI B DOGULU F
Citation
N. Turkozkan et al., THE EFFECT OF 2-CHLOROADENOSINE ON THE ATP LEVEL NA,K-ATPASE ACTIVITYIN EXPERIMENTAL BRAIN ISCHEMIA OF GERBIL, General pharmacology, 27(1), 1996, pp. 165-166
Citations number
20
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
General pharmacology → ACNP
ISSN journal
03063623
Volume
27
Issue
1
Year of publication
1996
Pages
165 - 166
Database
ISI
SICI code
0306-3623(1996)27:1<165:TEO2OT>2.0.ZU;2-5
Abstract
T1. The effect of 2-chloroadenosine, an adenosine analogue, on brain A TP level and Na,K ATPase activity in ischemia and reperfusion was stud ied. 2. Na,K ATPase activity decreased in both ischemia and reperfusio n. Although the ATP level decreased in ischemia, it increased with rep erfusion (P < 0.05). 3. It is concluded that 2-chloroadenosine treatme nt influenced ATP production and Na,K ATPase activity in ischemia and reperfusion (P < 0.05).