In a group of 54 bitches with pyometra, 31 per cent showed bilirubinur
ia. Bilirubinuria was associated with higher values of white blood cel
ls and serum haptoglobin, higher serum levels of alkaline phosphatase
and cholesterol and a higher serum aspartate aminotransferase/alanine
aminotransferase ratio, but not with a higher degree of anaemia (simil
ar PCV values). Bilirubinuria in bitches with pyometra is attributed t
o a higher degree of cholestasis associated with a greater inflammator
y reaction.