We evaluated four nasal cannulae used to deliver oxygen and measure PE
TCO(2) in a non-tracheally intubated, healthy population. The effect o
f various oxygen flow rates on PETCO(2) and respiratory rate (RR), as
well as the cost and relative patient comfort of the cannulae, was com
pared. In this controlled study, 20 healthy volunteers tested the cann
ulae using oxygen flow rates of 0 (breathing room air), 2, 4, and 6 L/
min. The volunteers rated the comfort of each cannula on a scale from
1 (uncomfortable) to 10 (comfortable). Hospital costs of the cannulae
were also compared. All of the cannulae, except the Hospitak nasal can
nula (HOS), demonstrated an oxygen flow dependency with respect to PET
CO(2) and RR. The HOS cannula was judged by the study population to be
the most comfortable and was the second least expensive cannula teste
d. From a qualitative standpoint, the carbon dioxide waveform recorded
with the HOS cannula was the one least affected by oxygen flow. Of th
e nasal cannula systems evaluated in this study, the HOS system demons
trated the best cost-benefit ratio, performing well clinically while b
eing comfortable to wear and relatively inexpensive. These conclusions
are specific to a healthy population and not to patients with lung di
sease, those who smoke, or those having a higher ASA classification st
atus. Our evaluation suggests that comfort and clinical performance of
nasal cannulae may well depend on device design.