He. Cline et al., SIMULTANEOUS MAGNETIC-RESONANCE PHASE AND MAGNITUDE TEMPERATURE MAPS IN MUSCLE, Magnetic resonance in medicine, 35(3), 1996, pp. 309-315
Noninvasive magnetic resonance temperature maps that are used to monit
or thermal ablation of tissue are described, In magnetic resonance ima
ges, thermally induced proton nuclear magnetic resonance frequency shi
fts, and changes in the longitudinal relaxation time produce both phas
e and magnitude changes in the MR signal, Temperature maps with improv
ed sensitivity are derived from the complex-difference nuclear magneti
c resonance signal. Bovine muscle specimens were heated with focused u
ltrasound to model thermal surgery and create a known thermal distribu
tion to test the method, Resulting MR images acquired in 2 s produce t
emperature maps with 1 mm resolution and 2 degrees C temperature sensi
tivity. The temperature sensitivity was increased by extending the acq
uisition to 5 s, by decreasing the receiver bandwidth, and increasing
the echo time.