Purpose: To evaluate the effect of buffered lidocaine with self report
ing of pain elicited during maxillary labial and palatal infiltrations
of permanent canines. Materials and Methods: A standardized, prospect
ive clinical trial of adult volunteers using a cross-over design of 20
paired injections using conventional 2% lidocaine with 1:100,000 epin
ephrine as the control. Results: Failed to establish a significant red
uction in pain scores for either injection site when buffered lidocain
e was injected intraorally.