ANTIMICROBIAL SUSCEPTIBILITY OF SUBGINGIVAL PORPHYROMONAS-GINGIVALIS ISOLATES FROM NORWEGIAN, SUDANESE AND ROMANIAN ADULT PERIODONTITIS PATIENTS

The epsilometer (E) test was used to evaluate the antimicrobial suscep tibility of 99 isolates of Porphyromonas gingivalis recovered from sub gingival plaque of adult periodontitis patients in Norway (20 isolates ), Sudan (39 isolates), and Romania (40 isolates). The antimicrobial a gents tested were penicillin G, clindamycin, erythromycin, amoxicillin , tetracycline, and metronidazole. Except for one Sudanese isolate whi ch had intermediate MIC value to erythromycin, results showed that all isolates from the three countries were sensitive to all six antibioti cs used. Pencillin G, clindamycin, and amoxicillin were the most effec tive. Erythromycin was the least effective antibiotic and, like tetrac ycline and metronidazole, it exhibited variable efficacy against isola tes from the three populations.