On the surface, the cardiac pacing lead is just a simple cable that co
nnects the pulse generator to the heart. The simple appearance of the
lead is very misleading, however. The size, longevity, and features of
the pulse generator and the patient's safety depend to a large extent
on the performance, of the lead. The pacemaker must assure that the h
eart will contract with each stimulus. Thus the pacemaker must deliver
a pulse of sufficient voltage and duration to stimulate with a suffic
ient safety factor to cope with ally minute-to-minute variations that
may occur in daily life. At the same time, it is necessary to use as l
ittle current as possible to maintain as long a battery longevity as i
s practical. The most common approaches to the problem of reliably del
ivering a stimulus with adequate safety margin while decreasing the cu
rrent drained from the battery have traditionally centered around elec
trode size, materials, surface structure, shape, and more recently, gl
ucocorticosteroid sustained release. Relatively little effort has been
directed toward optimizing the stimulus waveform for treatment of Bra
dy arrhythmias.