Al. Kellermann et al., IMPACT OF 1ST-RESPONDER DEFIBRILLATION IN AN URBAN EMERGENCY MEDICAL-SERVICES SYSTEM, JAMA, the journal of the American Medical Association, 270(14), 1993, pp. 1708-1713
Objective.-To evaluate the impact of adding first-responder defibrilla
tion by fire-fighters to an existing advanced life-support emergency m
edical services system. Design.-Nonrandomized, controlled clinical tri
al with periodic crossover. Setting.-Memphis, Tenn, a city of 610337 p
eople, which is served by a fire department-based emergency medical se
rvices system. All city ambulances provide advanced life support. Pati
ents.-Adult victims of out-of-hospital cardiac arrest due to heart dis
ease. Intervention.-Twenty of 40 participating engine companies were e
quipped with an automated external defibrillator and ordered to apply
it immediately in all cases of cardiac arrest. The other 20 companies
were ordered to start cardiopulmonary resuscitation (CPR) immediately
and wait for paramedics to arrive. Every 75 days, group roles were rev
ersed. Care otherwise proceeded according to 1986 American Heart Assoc
iation guidelines. Main Outcome Measures.-Return of spontaneous circul
ation in the field, survival to hospital admission, survival to hospit
al discharge, and neurological status at discharge. Results.-During th
e 39-month study interval, 879 patients were treated by a project engi
ne company. Four hundred thirty-one (49%) of these were found in ventr
icular fibrillation. Bystander CPR was started in only 12% of cases. O
verall, firefighters reached the scene a mean of 2.5 minutes faster th
an simultaneously dispatched paramedics. Although our automated extern
al defibrillators proved to be reliable and efficacious for terminatin
g ventricular fibrillation and pulseless ventricular tachycardia, pati
ents treated by an automated external defibrillator-equipped engine co
mpany were no more likely than CPR-treated controls to be resuscitated
(32% vs 34%, respectively), to survive to hospital admission (31% vs
29%), or to survive to hospital discharge (14% vs 10%). Neurological o
utcomes were also, similar in the two treatment groups. Conclusions.-I
n a fast-response, urban emergency medical services system served by p
aramedics, the impact of adding first-responder defibrillation appears
to be small. Early defibrillation alone cannot overcome low community
rates of by-stander CPR. Careful attention to every link in the ''cha
in of survival'' is needed to achieve optimal rates of survival after
cardiac arrest.