This study identified the ENT symptoms of 66 HIV infected children ove
r an 8 year period (1986-1993) at Great Ormond Street Hospital for Chi
ldren. The incidence, nature and age of onset of ENT symptoms were inv
estigated; 91% of the children had ENT symptoms, the most common being
cervical lymphadenopathy, oro-oesophageal candidiasis and otitis medi
a. The HIV infected children suffered from the common ENT diseases of
childhood. They also presented with specific conditions such as diffus
e parotid swelling. Therefore, their clinical features differed from H
IV infected adults as well as non-infected children. An increasing inc
idence of paediatric HIV infection was demonstrated by the study. Most
were due to vertical transmission. ENT surgeons are likely to see mor
e HIV infected children in future, either with the usual ENT diseases
of childhood (to which they seem more susceptible) or with HIV-specifi
c conditions. Although the diagnosis of HIV may be known, the ENT cond
ition could be the initial presentation suggestive of immunodeficiency
.