A SINGLE-ELEMENT MEDIATES GLUCOCORTICOID HORMONE RESPONSE OF HPV18 WITH NO FUNCTIONAL INTERACTIONS WITH AP1 OR HBRM

Authors
MEDINAMARTINEZ O MORALESPEZA N YANIV M GARCIACARRANCA A THIERRY F
Citation
O. Medinamartinez et al., A SINGLE-ELEMENT MEDIATES GLUCOCORTICOID HORMONE RESPONSE OF HPV18 WITH NO FUNCTIONAL INTERACTIONS WITH AP1 OR HBRM, Virology, 217(1), 1996, pp. 392-396
Citations number
30
Categorie Soggetti
Virology
Journal title
Virology → ACNP
ISSN journal
00426822
Volume
217
Issue
1
Year of publication
1996
Pages
392 - 396
Database
ISI
SICI code
0042-6822(1996)217:1<392:ASMGHR>2.0.ZU;2-X
Abstract
We determined that the human papillomavirus type 18 (HPV18) regulatory region contains one functional GRE sequence that interacts with the g lucocorticoid receptor. This sequence conferred a moderate hormonal ac tivation to the HPV18 P-105 promoter. Two modulators of glucocorticoid hormone activity, AP1 and hbrm, both involved in P-105 transcription, were found not to interfere with this hormonal activation. (C) 1996 A cademic Press, Inc.