BACTERIAL-RESISTANCE AND MANAGEMENT OF NO SOCOMIAL INFECTIONS - ARE THERE SPECIFIC PROBLEMS IN HEMATOLOGY

Because they receive many infected patients with various degrees of im munosuppression, the haematology departments have a high consumption o f antibiotics. The possible relationship between antibiotic consumptio n and bacterial resistance is discussed in many specialities, especial ly for some classes like quinolones. This possible relationship has to be evocated in haematology where patients are at high risk of severe sepsis because of neutropenia. In Henri Mondor hospital, we studied th e evolution of bacterial susceptibility and of antibiotic consumption in the haematology unit on a 6 year period. We found that this suscept ibility was finally stable over time. The main factors which may influ ence the evolution of the bacterial susceptibility in our study, and i n the literature are discussed.