DETERMINATION OF TRACE-ELEMENTS IN HUMAN SERUM BY INDUCTIVELY-COUPLEDPLASMA-ATOMIC EMISSION-SPECTROMETRY WITH FLOW-INJECTION

An analytical method for the simultaneous determination of some trace elements (Au, Fe, Mg, Li Sr, Zn) in human serum by inductively coupled plasma atomic emission spectrometry (ICP-AES) with flow injection is described. Physical interference caused by the change of sample viscos ity is discussed. When 100 mu l of serum was injected, the relevant re coveries of > 99% for Li, > 98% for Cu and Mg, > 95% for Fe were obtai ned for an NIST SRM with R.S.D. < 1.3% using optimized flow injection parameters. The prepared lyophilized control serum for routine analysi s in clinical laboratories was analyzed and verified for the validity of the technique employed in this experiment using NIST SRM 909 as a p rimary reference material.