Aud. Bode et al., THE EFFECTS OF EXTRACTS FROM TETRAPLEURA-TETRAPTERA (TAUB) AND BAYLUSCIDE(R) ON CELLS AND TISSUE STRUCTURES OF BIOMPHALARIA-GLABRATA (SAY), Journal of ethnopharmacology, 50(2), 1996, pp. 103-113
Subchronic experiments were conducted with low concentrations of sapon
ins from Tetrapleura tetraptera and Bayluscide(R) to study the ultrast
ructural effects of these molluscicides on Biomphalaria glabrata. The
ratio of the digestive cells to the crypt cells was inverted in mollus
cicide treated snails which showed an increase in the number of secret
ory cells and a decrease in the number of digestive cells. In the snai
l foot connective tissues, dose-dependent autolytic areas were observe
d. The major ultrastructural effects were seen in the digestive gland
with dose-dependent autolysis of the membranous structures such as the
golgi apparatus, mitochondria and endoplasmic reticulum. The results
show that the molluscicides produced non-specific effects on the membr
anous structures.