As part of a European Commission-funded research project on medical im
age analysis, we have developed a system aimed at solving a real clini
cal problem: the outlining of the target volume and organs at risk for
three-dimensional conformal radiation treatment planning. The clinica
l requirement is to make this process less tedious and time-consuming.
We show how object-oriented design techniques can be used to good eff
ect in a collaborative project such as this, so that image segmentatio
n and other algorithms from a number of different partners in the cons
ortium can be integrated into one system for comparative evaluation by
the clinical partners. We describe in some detail two of these algori
thms, one a straightforward region and volume grower, in which particu
lar attention has been paid to adapting the user interface to suit cli
nical needs, and the other an interactive tool using b-spline surface
patches for direct three-dimensional segmentation. We report on the cl
inical feedback we have received, which indicates that the most techni
cally advanced algorithms are not necessarily the most useful from a c
linician's point of view.