IN-VITRO ACTIVITIES OF OXAZOLIDINONE COMPOUNDS U100592 AND U100766 AGAINST STAPHYLOCOCCUS-AUREUS AND STAPHYLOCOCCUS-EPIDERMIDIS

Authors
KAATZ GW SEO SM
Citation
Gw. Kaatz et Sm. Seo, IN-VITRO ACTIVITIES OF OXAZOLIDINONE COMPOUNDS U100592 AND U100766 AGAINST STAPHYLOCOCCUS-AUREUS AND STAPHYLOCOCCUS-EPIDERMIDIS, Antimicrobial agents and chemotherapy, 40(3), 1996, pp. 799-801
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
40
Issue
3
Year of publication
1996
Pages
799 - 801
Database
ISI
SICI code
0066-4804(1996)40:3<799:IAOOCU>2.0.ZU;2-S
Abstract
The new oxazolidinone antimicrobial agents U100592 and U100766 demonst rated good in vitro inhibitory activity against clinical strains of St aphylococcus aureus and Staphylococcus epidermidis regardless of methi cillin susceptibility. Both agents appeared bacteriostatic by time-kil l analysis. Stable resistance to low multiples of the MIC of either dr ug could be produced only in methicillin-resistant S. aureus.