BLEOMYCIN THERAPY OF EXPERIMENTAL DISSEMINATED CANDIDIASIS IN MICE

Authors
GRAYBILL JR BOCANEGRA R FOTHERGILL A RINALDI MG
Citation
Jr. Graybill et al., BLEOMYCIN THERAPY OF EXPERIMENTAL DISSEMINATED CANDIDIASIS IN MICE, Antimicrobial agents and chemotherapy, 40(3), 1996, pp. 816-818
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
40
Issue
3
Year of publication
1996
Pages
816 - 818
Database
ISI
SICI code
0066-4804(1996)40:3<816:BTOEDC>2.0.ZU;2-D
Abstract
Bleomycin, an antineoplastic agent, was found to be very effective in vitro against a variety of fungi, including Candida albicans. Mice wer e infected with C. albicans intravenously and then treated with variou s doses of bleomycin. No efficacy was shown by either prolongation of survival or reduction of tissue counts.