THE BCL-I POLYMORPHISM OF THE HUMAN UNCOUPLING PROTEIN (UCP) GENE IS DUE TO A POINT MUTATION IN THE 5'-FLANKING REGION

Authors
CASSARDDOULCIER AM BOUILLAUD F CHAGNON M GELLY C DIONNE FT OPPERT JM BOUCHARD C CHAGNON Y RICQUIER D
Citation
Am. Cassarddoulcier et al., THE BCL-I POLYMORPHISM OF THE HUMAN UNCOUPLING PROTEIN (UCP) GENE IS DUE TO A POINT MUTATION IN THE 5'-FLANKING REGION, International journal of obesity, 20(3), 1996, pp. 278-279
Citations number
5
Categorie Soggetti
Nutrition & Dietetics","Endocrynology & Metabolism
Journal title
International journal of obesity → ACNP
ISSN journal
03070565
Volume
20
Issue
3
Year of publication
1996
Pages
278 - 279
Database
ISI
SICI code
0307-0565(1996)20:3<278:TBPOTH>2.0.ZU;2-6
Abstract
The polymorphic Bcl I site in the human ucp gene associated to percent age fat gain over time in the Quebec Family Study cohort (Oppert at al . Int J Obesity 1994; 18: 526-531) has been positioned to the 5'-flank ing region. This polymorphism results from a unique A/G mutation. Olig onucleotides used to amplify the polymorphic region. and allowing futu re studies of any cohort of patients, are described.