HYDROPHILIC INTERACTION CHROMATOGRAPHY ON AMINO-SILICA PHASES COMPLEMENTS REVERSED-PHASE HIGH-PERFORMANCE CHROMATOGRAPHY AND CAPILLARY ELECTROPHORESIS FOR PEPTIDE ANALYSIS

Authors
OYLER AR ARMSTRONG BL CHA JY ZHOU MX YANG Q ROBINSON RI DUNPHY R BURINSKY DJ
Citation
Ar. Oyler et al., HYDROPHILIC INTERACTION CHROMATOGRAPHY ON AMINO-SILICA PHASES COMPLEMENTS REVERSED-PHASE HIGH-PERFORMANCE CHROMATOGRAPHY AND CAPILLARY ELECTROPHORESIS FOR PEPTIDE ANALYSIS, Journal of chromatography, 724(1-2), 1996, pp. 378-383
Citations number
15
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography → ACNP
Volume
724
Issue
1-2
Year of publication
1996
Pages
378 - 383
Database
ISI
SICI code
Abstract
Hydrophilic interaction chromatography (HILIC) on amine bonded-phase s ilica columns provides separations of peptides that are complementary to those obtained with reversed-phase HPLC and free solution capillary electrophoresis. This is illustrated with the peptide drug atosiban a nd nine diastereomers. Moreover, one of the HILIC methods was suitable for coupling with electrospray mass spectrometry.