NEW PERSPECTIVES OF DESHCHEREVSKYS KINETI C-THEORY OF MUSCLE-CONTRACTION

Deshcherevsky's kinetic theory of muscle contraction (Deshcherevsky, 1 968,1971) is considered in the light of the modern experimental data. The data are discussed, which support the validity of; some propositio ns and conclusions of the theory, including the postulate on the negli gibly small probability of pulling crossbridge detachment. It is shown that if this postulate is accepted and the distance between the neigh bouring actin sites for the given myosin cross-bridge attachment on th e actin filament is taken as an actin filament hulf-turn (Sydorenko, 1 982, 1984), then simple explanations, which don't contradict the cross -bridge hypothesis of force generation, could be given to a number of muscle behaviour features such as the high efficiency, stepwise shorte ning, repeated tension recovery after repeated forced step-wise shorte ning of activated muscle with the time - interval less than 10 ms, ste p-size up to 90nm powered by a single ATP molecule and so on.