A new diterpenoid alkaloid cossonidine (1) has been isolated from Delp
hinium cossonianum and Delphinium cadiopetalum. The structure of cosso
nidine was determined by spectroscopic methods, including H-1 COSY, HM
QC, HMBC, and ROESY NMR experiments, and chemical transformations. The
NMR data of kobusine (5) and sanyonamine (6) are also presented.