OBOVAMINE, A NEW INDOLE ALKALOID FROM STEMMADENIA-OBOVATA

Authors
MADINAVEITIA A REINA M DELAFUENTE G GONZALEZ AG VALENCIA E
Citation
A. Madinaveitia et al., OBOVAMINE, A NEW INDOLE ALKALOID FROM STEMMADENIA-OBOVATA, Journal of natural products, 59(2), 1996, pp. 185-189
Citations number
23
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
2
Year of publication
1996
Pages
185 - 189
Database
ISI
SICI code
0163-3864(1996)59:2<185:OANIAF>2.0.ZU;2-7
Abstract
The stem bark of the Panamanian plant Stemmademia obovata has afforded a new ibogaine-type alkaloid, obovamine (1), whose structure was dete rmined by a combination of spectral interpretation and chemical correl ations. Ten known alkaloids, coronaridine, coronaridine hydroxyindolen ine, voacangine, voacangine hydroxyindolenine, (19S)-heyneanine, (19S) -heyneanine hydroxyindolenine, (19S)-voacristine, (19S)-voacristine hy droxyindolenine, ajmalicine, and ajmalicinine, were also isolated. Voa cangine was the main alkaloid constituent.