BRONCHOPULMONARY AND DISSEMINATED GRANULOMATOUS-DISEASE ASSOCIATED WITH ASPERGILLUS-FUMIGATUS AND CANDIDA SPECIES INFECTION IN A GOLDEN RETRIEVER

A seven-year-old, female golden retriever was referred for a paroxysma l, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uve itis, and deteriorating general condition. A severe, mixed interstitia l and alveolar pattern, with poorly defined amorphous lesions, was see n on thoracic radiographs. Multiple, whitish nodules disseminated on t he hyperemic respiratory mucosa were noted on bronchoscopy. Escherichi a coil and Aspergillus fumigatus were cultured from the bronchoalveola r lavage. Granulomatous lesions in numerous organs were identified dur ing necropsy, and Aspergillus fumigatus and Candida spp. were cultured from lung and kidney tissues. Microscopic granulomatous lesions were compatible with mycotic infection; however, fungal organisms were not observed.