Bone allografts as used in dentistry have a 20-year history of safety
and efficacy, Case reports and controlled clinical trials have shown t
he potential of both mineralized and decalcified cortical freeze-dried
bone allograft to reconstruct the bone defects caused by periodontiti
s, Histomorphometric analysis of human biopsies following grafts of de
calcified freeze-dried bone allograft have shown the ability of decalc
ified freeze-dried bone allograft to promote regeneration of new bone,
cementum, and periodontal ligament an a tooth root surface previously
exposed to bacterial plaque, The addition of mineralized freeze-dried
bone allograft and decalcified freeze-dried bone allograft to the gui
ded tissue and guided bone regeneration procedures have significantly
enhanced results, especially in large osseous lesions.