SYNTHESES OF 11-HYDROXYLATED GUAIANOLIDES

Authors
LAURIDSEN A CORNETT C VULPIUS T MOLDT P CHRISTENSEN SB
Citation
A. Lauridsen et al., SYNTHESES OF 11-HYDROXYLATED GUAIANOLIDES, Acta chemica Scandinavica, 50(2), 1996, pp. 150-157
Citations number
20
Categorie Soggetti
Chemistry,Biology
Journal title
Acta chemica Scandinavica → ACNP
ISSN journal
0904213X
Volume
50
Issue
2
Year of publication
1996
Pages
150 - 157
Database
ISI
SICI code
0904-213X(1996)50:2<150:SO1G>2.0.ZU;2-#
Abstract
Two epimeric guaianolides, both prepared from alpha-santonin, were 11- hydroxylated using 2-phenylsulfonyl-3-phenyloxaziridine as a reagent. Extensive use of protecting groups enabled selective acylation of the 3- and 10-hydroxy groups.