MODIFICATION OF THE EXTRACELLULAR-MATRIX FOLLOWING MYOCARDIAL-INFARCTION MONITORED BY FTIR SPECTROSCOPY

Authors
LIU KZ JACKSON M SOWA MG JU HS DIXON IMC MANTSCH HH
Citation
Kz. Liu et al., MODIFICATION OF THE EXTRACELLULAR-MATRIX FOLLOWING MYOCARDIAL-INFARCTION MONITORED BY FTIR SPECTROSCOPY, Biochimica et biophysica acta. Molecular basis of disease, 1315(2), 1996, pp. 73-77
Citations number
11
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Molecular basis of disease → ACNP
ISSN journal
09254439
Volume
1315
Issue
2
Year of publication
1996
Pages
73 - 77
Database
ISI
SICI code
0925-4439(1996)1315:2<73:MOTEFM>2.0.ZU;2-K
Abstract
Comparison of mid- and near-infrared spectra of control and infarcted rat ventricular tissue reveals the presence of absorptions in infarcte d tissue which are highly characteristic of collagen, indicating large scale deposition of type I collagen in the myocardium following infar ction. These results demonstrate that IR spectroscopy may be used to r apidly monitor the modifications of the extracellular matrix associate d with myocardial infarction.