EFFECT OF TEMPERATURE ON CRYSTAL-GROWTH AND CRYSTAL PROPERTIES OF PARACETAMOL

The crystal growth kinetics of paracetamol have been investigated at d ifferent temperatures and the crystals obtained have been analysed for their mechanical properties. Variations in the crystal habit and crys tal quality can be explained by different growth activation energies f or the most important crystallographic faces, {001} and {110}. The mag nitude of these energies corresponds to the anisotropy of the intermol ecular bonds in the crystal lattice. The crystallization temperature s trongly influences the thermodynamic and mechanical properties of para cetamol crystals.