ENANTIOMERIC RESOLUTION OF CHIRAL SULFOXIDES ON POLYSACCHARIDE PHASESBY HPLC

Authors
MATLIN SA TIRITAN ME CASS QB BOYD DR
Citation
Sa. Matlin et al., ENANTIOMERIC RESOLUTION OF CHIRAL SULFOXIDES ON POLYSACCHARIDE PHASESBY HPLC, Chirality, 8(1), 1996, pp. 147-152
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chirality → ACNP
ISSN journal
08990042
Volume
8
Issue
1
Year of publication
1996
Pages
147 - 152
Database
ISI
SICI code
0899-0042(1996)8:1<147:EROCSO>2.0.ZU;2-H
Abstract
The enantiomeric resolution of chiral sulfoxides was investigated on a mylose (S)-alpha-methylbenzyl carbamate phase coated on aminopropylate d 7 mu m silica with 500 Angstrom diameter pores. This was shown to be very successful in the separation of alkyl/aryl, aryl/aryl, and non-a romatic sulfoxides. The effect of pore size using naked silica was als o investigated, demonstrating that the pore size does not affect the r esolution. (C) 1996 Wiley-Liss, Inc.