AN EFFICIENT PREPARATION OF COUMARINS

Authors
ROUESSAC F LECLERC A
Citation
F. Rouessac et A. Leclerc, AN EFFICIENT PREPARATION OF COUMARINS, Synthetic communications, 23(19), 1993, pp. 2709-2715
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
23
Issue
19
Year of publication
1993
Pages
2709 - 2715
Database
ISI
SICI code
0039-7911(1993)23:19<2709:AEPOC>2.0.ZU;2-9
Abstract
o-methoxyaryl-aldehydes (or -ketones) react in solid-phase with Meldru m's acid under mild conditions, to give benzylidene derivatives which are cyclized in high yield, with cold sulfuric acid to substituted 3-c arboxycoumarins. Thermal decarboxylation, speed up by copper powder, p rovided an easy access to numerous coumarins.