Data from the National Cancer Registry of Slovakia were used to evalua
te survival for 2,958 childhood cancer patients registered between 196
8 and 1987 and aged 0-14 years at diagnosis. Actuarial survival rates
were computed for children diagnosed in 4 successive 5-year periods an
d compared. Overall 5-year survival rose from 20% for the period 1968-
1972 to 46% for the period 1983-1987. The increase was statistically s
ignificant in age groups 1-4, 5-9 and 10-14 years. Survival for childr
en aged less than year also increased slightly, but this was not stati
stically significant. In most of the major diagnostic groups, survival
increased markedly. Five-year survival rose significantly for leukaem
ias, lymphomas, CNS neoplasms, Wilms' tumours, bone tumours, soft-tiss
ue sarcomas and germ-cell tumours. Despite this progress, survival in
Slovakia remains lower than the corresponding figures from registries
in Western Europe and the United States. (C) 1996 Wiley-Liss, Inc.