A. Ikeda et al., REGIOSELECTIVE INTRAMOLECULAR-BRIDGING OF CALIX[8]ARENES - UNEXPECTEDISOLATION OF A DOUBLY-BRIDGED UNIMOLECULAR CAPSULE-LIKE COMPOUND, Tetrahedron letters, 37(10), 1996, pp. 1621-1624
We report new methods for the synthesis of intramolecularly-bridged ca
lix[8]arenes by bis(bromomethyl) reagents. We could isolate not only s
ingly-bridged compounds but also a doubly-bridged compound. The doubly
-bridged compound has a unique capsule-like structure, the cavity of w
hich consists of eight phenolic oxygens.