AN ENANTIOSELECTIVE ROUTE TO PYRROLIDINES - REMOVAL OF THE CHIRAL TEMPLATE FROM HOMOCHIRAL PYRROLOIMIDAZOLES

Authors
JONES RCF HOWARD KJ SNAITH JS
Citation
Rcf. Jones et al., AN ENANTIOSELECTIVE ROUTE TO PYRROLIDINES - REMOVAL OF THE CHIRAL TEMPLATE FROM HOMOCHIRAL PYRROLOIMIDAZOLES, Tetrahedron letters, 37(10), 1996, pp. 1711-1714
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
10
Year of publication
1996
Pages
1711 - 1714
Database
ISI
SICI code
0040-4039(1996)37:10<1711:AERTP->2.0.ZU;2-E
Abstract
Two-step reductive removal of the chiral template from optically activ e pyrroloimidazoles, available from 1,3-dipolar cycloaddition of homoc hiral imidazolinium ylides, gives optically active substituted pyrroli dines. Selective manipulation of the substituents affords, e.g. natura lly occurring proline derivatives and homochiral pyrrolizidines.