MODELING OF ION-PAIRING EXTRACTION WITH QUATERNARY AMINES

The objective of this work is to present a general methodology and to describe the modeling of ion-pairing extraction of organic acids, incl uding amino acids, with quaternary amines, allowing for the prediction of equilibrium concentrations with different operating conditions. Th e model takes into account the hydration of the organic phase, thus ma king it also valid for any organic phase used. A rational design of th e operating conditions to be used to optimize extraction and stripping is then possible from simulation studies. The model developed is test ed by comparing predictions of equilibrium concentrations with experim ental studies using lactate extraction with different amine concentrat ions. Validation is extended to the stripping process using chloride a s the counterion; the model thus obtained adequately describes the ext raction and stripping of lactate.