SYNTHESIS OF RAPAMYCIN PEPTIDE HYBRID MOLECULE (RAP-P) - HIGH-AFFINITY FKBP12 LIGAND

Authors
CHAKRABORTY TK HUSSAIN KA
Citation
Tk. Chakraborty et Ka. Hussain, SYNTHESIS OF RAPAMYCIN PEPTIDE HYBRID MOLECULE (RAP-P) - HIGH-AFFINITY FKBP12 LIGAND, Tetrahedron, 52(11), 1996, pp. 4053-4064
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
11
Year of publication
1996
Pages
4053 - 4064
Database
ISI
SICI code
0040-4020(1996)52:11<4053:SORPHM>2.0.ZU;2-K
Abstract
The syntheses of two rapamycin-peptide hybrid molecules RAP-P (5 and 6 ) containing the rapamycin-FK 506-ascomycin binding domain and differe nt peptide tethers are described in detail.