B. Heckmann et al., CHIRAL ACETALS - STEREOCONTROLLED SYNTHESES OF 16-HYDROXYEICOSATETRAENOIC, 17-HYDROXYEICOSATETRAENOIC, AND 18-HYDROXYEICOSATETRAENOIC ACIDS, CYTOCHROME-P-450 ARACHIDONATE METABOLITES, Tetrahedron letters, 37(9), 1996, pp. 1425-1428
Chiral adducts from Grignard or allylsilane additions to 1,3-dioxan/1,
3-dioxolan-4-ones were exploited for the total synthesis of the R- and
S-isomers of the title eicosanoids.