Localized outbreaks of meningococcal disease in the United States and
Canada continue to cause serious alarm within communities as a result
of the fulminating pattern of the disease, high mortality rate, and hi
gh incidence among adolescents. The increasing number of outbreaks sin
ce 1991 has raised questions about the management and prevention of fu
rther cases during an outbreak. The purpose of this statement is to gu
ide primary-care physicians in their role in infection control and pre
vention of both sporadic cases and outbreaks of invasive meningococcal
disease. This statement provides information on the epidemiology of m
eningococcal disease, including definitions of sporadic, secondary, an
d coprimary cases, clusters of cases, and outbreaks. Data are presente
d on identification of cases, disease risk of contacts, and agents for
chemoprophylaxis, and recommendations are given for: (I) risk assessm
ent of contacts, (2) administration of chemoprophylaxis, (3) appropria
te use of meningococcal. vaccine, (4) appropriate use of the microbiol
ogy laboratory, (5) the necessity for timely and appropriate reporting
of invasive meningococcal disease to local public health authorities,
and (6) information on counseling and public education that may be he
lpful during an outbreak to minimize public anxiety. An additional sec
tion, ''Information for Sharing,'' which uses a question-and-answer fo
rmat and which may be helpful to parents and community and health care
workers during an outbreak, is also provided.