PROPHYLAXIS USING PAROMOMYCIN OF NATURAL CRYPTOSPORIDIAL INFECTION INNEONATAL KIDS

The chemoprophylactic effects of paromomycin sulfate against natural c ryptosporidiosis in young kids were investigated. Two studies were car ried out using two groups of 18 and 12 animals in two pens. In each pe n, kids were allocated to treated or control groups, The treatment con sisted of oral paromomycin given at 100 mg kg(-1) body weight day(-1) for 11 consecutive days from 2 days of age. All kids were weighed at 2 , 6 and 10 days of age, Infection was monitored by collecting fecal sa mples and staining fecal smears every 3-4 days from days 4 or 5 to day s 15 or 19. The results clearly showed the efficacy of paromomycin in reducing cryptosporidial oocyst output, Moreover, paromomycin prevente d clinical signs and mortality.