Human immunodeficiency virus (HIV) infection has been associated with
several renal disorders. Thrombotic thrombocytopenic purpura/hemolytic
uremic syndrome (TTP/HUS) were also described in several patients wit
h overt AIDS. We describe a patient who presented with HUS and only su
bsequent investigation to find the cause of HUS led to the diagnosis o
f HIV infection. HIV infection should be suspected in patients present
ing with microangiopathic renal failure.