SUCCESSFUL TREATMENT OF BOTRYOID RHABDOMYOSARCOMA IN THE BLADDER OF ADOG

A 10-month-old male Labrador retriever with a 10-week history of stran guria, pollakiuria, hematuria, and urine retention had a large botryoi d rhabdomyosarcoma resected from the trigonal region of the urinary bl adder. Resection was aided by submucosal injection of saline to establ ish a dissection plane. A cuff of the ureteral mucosa was sutured to t he bladder wall in an attempt to prevent ureteral stricture. Postopera tive complications included urine retention due to stricture of the pr oximal urethra and rupture of the right renal pelvic collection system with urine extravasation. Balloon dilation corrected the urethral str icture, and the ruptured pelvic collection system resolved spontaneous ly. Adjuvant chemotherapy included four cycles of doxorubicin (30 mg/m 2 BSA IV) and cyclophosphamide (75 mg/m2 BSA PO on days 4, 5, 6, and 7 ). As no evidence of tumor recurrence was apparent 21 months after sur gery, this is the first reported instance of a prolonged clinical remi ssion for this tumor type in the dog.