Six cats were diagnosed with globule leukocyte tumors. There was no br
eed, sex, or age predilection. Primary complaints were nonspecific: an
orexia and weight loss. The most common physical examination, finding
was a palpable mid- to cranial abdominal mass. Five were tested for fe
line leukemia virus, and all were negative. Clinical course and respon
se to chemotherapy varied widely. Necropsy findings demonstrated exten
sive metastatic potential for this neoplasm. This report indicated tha
t the prognosis may not be as poor as previous reports would indicate.